Microbiological Characteristics and Resistance Patterns in a Neonatal Intensive Care Unit: A Retrospective Surveillance Study

This study examines the prevalence and antimicrobial susceptibility patterns of bacterial infections in neonates with early-onset sepsis (EOS) and late-onset sepsis (LOS). Results show LOS has a higher incidence (94.43%) compared to EOS (5.56%). The leading isolates are gram-positive bacteria, with coagulase-negative Staphylococci (CONS) being predominant in LOS cases (42.9%). The study found reduced resistance levels of CONS against various antibiotics, suggesting that current antibiotics provide adequate coverage against prevalent bacteria.